Doctor of Philosophy

Application Deadline: 1/15/2010

The Oral Biology Ph.D. program usually requires five years. Students are expected to devote the full twelve-month year to their graduate work (allowing time for vacation and holidays). Graduate students will have the opportunity to assist in the teaching program of the department as a practical means of gaining experience in the presentation of lectures and laboratory work.

Courses

The course requirement is a minimum of 90 credits (including at least 27 credits of thesis). Through their coursework, students are expected to gain proficiency in one or more basic biologic sciences and to master modern biological approaches in addition to gaining expertise in the subject area of oral and craniofacial sciences. At least 15 credit hours must come from science courses in departments other than Oral Biology. These will include courses offered through the Molecular and Cell Biology Program and courses selected to match the basic science interests of the student. Cross-disciplinary training in Bioengineering is also available. All graduate students are also expected to attend and participate in departmental seminars (ORALB 575).

Path to Ph.D

The Following is an approximate timeline for completion of the Ph.D. degree. Because each student's program and research goals will vary, completion of the requirements for the Ph.D. degree may not necessarily follow this timeline.

Year 1

Initial Course Work

All new students meet with the Graduate Program Coordinator before the start of classes in the Autumn Quarter to consider the student's course work. The selection of courses will depend on the student's background, research goals, and interests.

All new students meet with the Graduate Program Coordinator before the start of classes in the Autumn Quarter to consider the student's course work. The selection of courses will depend on the student's background, research goals, and interests.

Research Rotation

During each quarter of the first year of graduate study, the student will register for ORALB 578, Research Techniques. The purpose of this course is for students to carry out research projects in the laboratories of several faculty members in order to prepare for the choice of their Ph.D. project mentor and to learn a variety of research methods. Each student is expected to take 2-3 rotations in different laboratories and select a research mentor by the end of the 1st year.

Year 2

Course Work

Students will continue to take courses that will include the remainder of the core courses required in Oral Biology and courses in other disciplines relevant to the student's dissertation research.

Teaching

Students are encouraged to take elective courses offered through the Medical Education and Graduate School which will help them in their future teaching careers. Also, beginning in the second year, graduate students will have the opportunity to take part in teaching one of the Department courses for undergraduate dental students. This experience prepares students for teaching responsibilities after receipt of the Ph.D. and provides a good opportunity for consolidation of the student's general oral biology background.

Research

Early in the second year of study, the student is expected to choose a thesis adviser and to define a dissertation problem.

Supervisory Committee

Once a thesis mentor and research direction have been chosen, the student and mentor will select a Supervisory Committee. This should be done in year two or by the third year at the latest. The committee is composed of at least four faculty members, at least three of whom (Including the Chair and the Graduate School Representative) must be members of the Graduate Faculty with an endorsement to chair doctoral committees. The Graduate Program Coordinator will forward the list of recommended committee members to the Dean of the Graduate School who will officially appoint the Supervisory Committee. In accordance with Graduate School regulations, the Supervisory Committee will be responsible for advising and directing the student through the Ph.D. program.

Year 3

General Examination

By the end of the third year, the student will take the General Examination. This examination is in the format of a written research grant proposal that is presented to the Ph.D. supervisory committee.  All required coursework must be completed at this time. The purposes of this examination are (1) to determine whether the student is capable of recognizing an important research question in oral and craniofacial sciences, (2) to determine whether the student is able to develop this question into a comprehensive proposal complete with preliminary findings and suggested methods of procedure, and to orally defend the proposal, and (3) to provide the student an opportunity to receive feedback from the Supervisory Committee on the proposed research project.

Year 3 to Completion

The student will primarily engage in thesis research and additional advanced coursework.

The Dissertation and the Dissertation Examination

When the candidate has completed the research project, written the dissertation, and had it approved by the reading committee, the mentor will obtain approval from the Graduate School and set a date for the Final Examination. The Final Examination will be concerned principally with the subject matter of the dissertation and is conducted as an open seminar followed by examination by the Supervisory Committee.

The research project for the Ph.D. dissertation will be chosen by the candidate and adviser and be approved by the candidate's Supervisory Committee. The research must represent a worthy and fundamental contribution showing originality in concept and implementation.

Courses

Electives (Recommended)
Code Title Credits Offered
DPHS 568 Biostatistics in Dentistry 3 S
ORALB 569 Advanced Oral Microbiology 2 W
ORALB 575 Oral Biology Seminar 1-3, max. 30 A, Sp, W
ORALB 578 Research Techniques in Oral Biology 2-4, max. 15 A, Sp, S, W
ORALB 579 Molecular Biology 2 S
ORALB 580 Introduction to Molecular Biology Laboratory 4 A (Even Years)
ORALB 581 Secretory Process in Exocrine Glands 1-3, max. 3 Sp
ORALB 591 Advanced Topics in Oral Biology and Medicine I 1-2, max. 2 W
ORALB 592 Advanced Topics in Oral Biology and Medicine II 1-2, max. 2 Sp
ORALB 600 Independent Study or Research * A, Sp, S, W
ORALB 800 Doctoral Dissertation * A, Sp, S, W

Students are expected to take additional courses in bioengineering, epidemiology, immunology, or other basic biological/medical sciences as appropriate for their research interests. At least 6 such credits are required. The student will work with the Graduate Program Coordinator and their mentor (if chosen) to select appropriate elective courses in their chosen basic biological science pathway. The provided list is not meant to be exhaustive.

Code Title Credits Offered
BIOC 530 Introduction to Structural Biology 3 A
BIOEN 510 Bioengineering Seminars 1  
DPHS 569 Clinical Epidemiology and Study Design in Dentistry 2 S
GENOME 551 Principles of Gene Regulation 1.5  
GENOME 552 Technologies for Genome Analysis 1.5 A
GENOME 553 Advanced Genetic Analysis 1.5  
IMMUN 441 Introduction to Immunology 4 A
IMMUN 532 Advanced Immunology 4 W
MCB 511 Cell Cycle Control 3 A
MCB 521 Embryos, Genes and Development 4 W
MCB 542 Nucleic Acids and Enzymes 2 Sp
MICROM 445 Medical Virology 2 Sp
MICROM 510 Physiology of Bacteria 3 W (Odd Years)
MICROM 553 Molecular Mechanisms of Bacterial Pathogenesis 3 A (Odd Years)
NBIO 401 Systems Neurobiology 3 A
NBIO 402 Sensory Systems: From Molecules to Mind 3 W
NBIO 403 Systems and Behavioral Neurobiology 3 W
NBIO 404 Neuropharmacology 3 Sp
ORTHO 580 Functional Cranial Anatomy 3 S
PABIO 568 Molecular Epidemiology of Infectious Diseases 2 W
PERIO 575 Immunologic Aspects of Oral Diseases 2 W

Other Oral Biology Electives.

Code Title Credits Offered
ORALB 564 Clinical Oral Pathology 1-3 A, Sp, S, W
ORALB 565 Clinical Oral Pathology 1-3 A, Sp, S, W
ORALB 574 Clinical Stomatology 3 Sp
ORALB 577 Applied Therapeutics in Dentistry 2 A (Odd Years)

In order to prepare for teaching, it is strongly recommended that the student take at least one class on educational methods. Such credits will not fulfull the requirement for out-of-department science courses, but will count toward the total credits required. The provided list is not meant to be exhaustive.

Code Title Credits Offered
GRDSCH 630 Teaching and Learning in Higher Education 2, max. 6  
MEBI 520 Teaching Methods in Medical Education 2 W
MEBI 521 Evaluation of Learning in the Health Sciences 3 Sp
Required (6 Credits)

Students must also take at least 6 credits from the Molecular and Cell Biology Program (CONJ 524-551, typically 1.5 credits each) or Bioinformatics (PABIO 536, 3 credits). Because these courses are from outside Oral Biology, they (and DPHS 568 from the required courses listing) can be applied to the out-of-department requirement of 15 credits. The additional 6 required credits in science courses from outside Oral Biology can be selected from any appropriate program.

The following is a brief list of our conjoint offerings. For a complete and current list, go to the http://www.washington.edu/students/crscat/conj.html

Code Title Credits Offered
CONJ 514 Molecular Medicine 3 W
CONJ 524 Structural Basis of Signal Transduction 1.5 W
CONJ 526 Introduction to Systems Biology and Quantitative Approaches to Biomedical Sciences 1.5 W
CONJ 530 Directing Stem Cells Toward Regenerative Medical 1.5 Sp
CONJ 531 Signaling Mechanisms in Excitable Cells 1.5 A
CONJ 532 Signal Transduction from the Cell Membrane to the Nucleus 1.5 A
CONJ 533 The Dynamic Chromosome 1.5 A
CONJ 534 Selected Problems in Nervous System Development 1.5 W
CONJ 535 RNA Structure and Biological Function 1.5 W
CONJ 536 Experimental Design in Cell Biology 1.5 W
CONJ 537 Mechanism of Transcriptional Regulations 1.5 A
CONJ 538 Genetic Instability and Cancer 1.5 A
CONJ 539 Biological Basis of Neoplasia 1.5 S
CONJ 541 Molecular Biology of Cellular Processes 1.5 Sp
CONJ 542 Development 1.5 W
CONJ 544 Protein Structure, Modification and Regulation 1.5 W
CONJ 545 Molecular Interactions and Medicine 1.5 Sp
CONJ 546 Survey of Technologies for Molecular Biology 1.5 A
CONJ 547 Molecular Evolution of Viral-Host Interactions 1.5 Sp
CONJ 548 Modeling Proteins and Proteomes 1.5 W
CONJ 549 Microbial Population Biology 1.5 Sp (Even Years)
CONJ 551 Immunity 1.5 Sp
CONJ 552 Metabolic Flexibility in Biology 1.5  
PABIO 536 Bioinformatics and Gene Sequence Analysis 3 A, Sp
Prerequisites (Recommended)

Some students may need to take some lower level division courses in order to prepare for required classes. The following is a list of suggested prerequisite courses.

Code Title Credits Offered
BIOC 440 Biochemistry 4 A
BIOC 441 Biochemistry 4 W
BIOC 442 Biochemistry 4 Sp
BIOL 411 Developmental Biology 4 A, W
GENOME 411 Gene Action 5 W
IMMUN 441 Introduction to Immunology 4 A

Contacts

Jennifer Kohn
Counseling Services Coordinator
jkohn@u.washington.edu | 206-543-5477
Dr. Richard Presland, Ph.D.
Associate Professor & Graduate Program Director
rp@u.washington.edu | 206-616-6706
University of Washington © 2006 - 2009
1959 NE Pacific Street Seattle WA, 98195-7132
Building: Health Sciences | Room: B-224
Phone: 206-543-5477 | Fax: 206-685-3162 | oralb@u.washington.edu
Site Map | Feeds